Artemisinin

About Artemisinin 

Artemisia Annua Extract and some of the related compounds derived directly from the sweet wormwood herb, are sometimes referred to as Qinghaosu.These compounds, and their synthetic derivatives, have been described in The New York Times as “trikingly effective against malaria”. Artemisia Annua Extract has been used for centuries to kill parasites, particularly worms and flukes.

Artemisinin is isolated from the plant Artemisia annua, a herb described in Chinese traditional medicine. Artemisinin, also known as Qinghaosu, and its derivatives such as Artesunate, Artemether, Dihydroartemisinin, etc. are a group of drugs that possess the most rapid action of all current drugs against falciparum malaria.

Artemisinin appilication:

1.Artemisia Capillaris Extract Artemisinin Powder as pharmaceutical raw materials for clearing away heat, anti-inflammation, detumescence and more, it is mainly used in pharmaceutical field.

2.Artemisia Capillaris Extract Artemisinin Powder as products effective ingredients for improving blood circulation and soothing the nerves, it is mainly used in health product industry.

3.Artemisia Capillaris Extract Artemisinin Powder as active ingredients of skin care products, it is mainly used in cosmetic industry

Artemisinin main function:

1.Warm the period and stop bleeding, Anti-cruor.

2.Release the coldness and paining; 

3.External use for the remove the damp and itching . 

4.Anti-bacteria. Anti-virus. 

5.Stop coughing, relieving asthma,Eliminating phlegum. 

6.Improve the body immune system. 

7.Protect the liver and gull.

References:

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2.Aquil S, Husaini AM, Abdin MZ, Rather GM (2009) Overexpression of the HMG-CoA reductase gene leads to enhanced artemisinin biosynthesis in transgenic Artemisia annua plants. Planta Med 75:1453–1458

3.Banyai W, Kirdmanee C, Mii M, Supaibulwatana K (2010) Overexpression of farnesyl pyrophosphate synthase (FPS) gene affected artemisinin content and growth of Artemisia annua L. Plant Cell Tiss Organ Cult 103:255–265

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10.Lan XZ, Chang K, Zeng LJ, Liu XQ, Qiu F, Zheng WL, Quan H, Liao ZH, Chen M, Huang WL, Liu WH, Wang Q (2013) Engineering salidroside biosynthetic pathway in hairy root cultures of Rhodiola crenulata based on metabolic characterization of tyrosine decarboxylase. PLoS One 8:e75459

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12.Lu X, Zhang L, Zhang FY, Jiang WM, Shen Q, Zhang LD, Lv ZY, Wang GF, Tang KX (2013a) AaORA, a trichome-specific AP2/ERF transcription factor of Artemisia annua, is a positive regulator in the artemisinin biosynthetic pathway and in disease resistance to Botrytis cinerea. New Phytol 198:1191–1202

13.Lu X, Jiang WM, Zhang L, Zhang F, Zhang FY, Shen Q, Wang GF, Tang KX (2013b) AaERF1 positively regulates the resistance to Botrytis cinerea in Artemisia annua. PLoS One 8:e57657

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23.Tang KX, Shen Q, Chen YF, Wang T, Wu SY, Lu X (2012a) Overexpression DBR2 gene increased artemisinin content in Artemisia annua L. Shanghai Jiao Tong University, Shanghai. Patent CN201210014227.2

24.Tang KX, Chen YF, Shen Q, Wang T, Wu SY, Wang GF (2012b) Overexpression ALDH1 gene increased artemisinin content in Artemisia annua L. Shanghai Jiao Tong University, Shanghai. Patent CN201210014242.7

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26.Wang HH, Ma CF, Li ZQ, Ma LQ, Ye HC, Xu GW, Liu BY (2010) Effects of exogenous methyl jasmonate on artemisinin biosynthesis and secondary metabolites in Artemisia annua L. Ind Crop Prod 31:214–218

27.Xiang LE, Zeng LX, Yuan Y, Chen M, Wang F, Liu XQ, Zeng LJ, Lan XZ, Liao ZH (2012) Enhancement of artemisinin biosynthesis by overexpressing dxr, cyp71av1 and cpr in the plants of Artemisia annua L. Plant Omics 5:503–507

28.Yu ZX, Li JX, Yang CQ, Hu WL, Wang LJ, Chen XY (2012) The jasmonate-responsive AP2/ERF transcription factors AaERF1 and AaERF2 positively regulate artemisinin biosynthesis in Artemisia annua L. Mol Plant 5:353–365

29.Zhang FY, Lu X, Lv ZY, Zhang L, Zhu MM, Jiang WM, Wang GF, Sun XF, Tang KX (2013) Overexpression of the Artemisia orthologue of ABA receptor, AaPYL9, enhances ABA sensitivity and improves artemisinin content in Artemisia annua L. PLoS One 8(2):e56697

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