About Apple extract:
Apple Extract is extracted from apple fruit. Apple polyphenols are phytochemicals concentrated in the skin of unripe apples.Quercetin, procyanidins, catechins,phloridzin,phloretin, epicatechin,rutin,and chlorogenic acid are all apple polyphenols.
These chemical compounds are being studied extensively in labs around the world for their health effects in major diseases. Apple polyphenols have been shown to be 2 to 6 times more powerful then Vitamin C as antioxidants. Apple polyphenols are naturally occurring plant compounds that act as potent antioxidants.
Apple extract phloretin Function:
1. Improve the body’s resistance to fight against diseases.
2. Prevent oxidative stress.
3. Reduce fat around body organs.
4. Build strong muscles.
5. Provide nutrition to the body.
6. Improve skin problems and skin disorders.
7. Assist in solving the problem of baldness in males.
8. Fight heart diseases.
Apple extract phloretin Application:
1. It can be used in Cosmetic fileld, such as facial mask, skin care cream, lotion and essence
2. It can be used in pharmaceutical Field.
3. It can be used in nutritional Supplement.
For more product information pls kindly contact email sales09@staherb.cn
Product Analysis:
| Items | Standards | Results |
| Physical Analysis | ||
| Description | Brown Yellow Powder | Complies |
| Assay | Phloretin | 50.25% |
| Mesh Size | 100 % pass 80 mesh | Complies |
| Ash | ≤ 5.0% | 2.65% |
| Loss on Drying | ≤ 5.0% | 3.85% |
| Chemical Analysis | ||
| Heavy Metal | ≤ 10.0 mg/kg | Complies |
| Pb | ≤ 2.0 mg/kg | Complies |
| As | ≤ 1.0 mg/kg | Complies |
| Hg | ≤ 0.1mg/kg | Complies |
| Microbiological Analysis | ||
| Residue of Pesticide | Negative | Negative |
| Total Plate Count | ≤ 1000cfu/g | Complies |
| Yeast&Mold | ≤ 100cfu/g | Complies |
| E.coil | Negative | Negative |
| Salmonella | Negative | Negative |
References:
1.Alvarez, O., Latorre, R. 1978. Voltage-dependent capacitance in bilayers made from monolayers.Biophys. J. 21:1–17
2.Andersen, O.S., Finkelstein, A., Katz, I., Cass, A. 1976. Effect of phloretin on the permeability of thin lipid membranes.J. Gen. Physiol. 67:749–771
3.Bangham, A.D. 1968. Membrane models with phospholipids.In: Progress in Biophysics and Molecular Biology. pp. 29–95. Pergamon Press, New York
4.Bihler, J., Cavert, H.M., Fisher, R.B. 1965. A differential effect of inhibitors on sugar penetration into the isolated rabbit heart.J. Physiol. (London) 180:168–177
5.Coster, H.G.L., Smith, J.R. 1974. The molecular organization of bimolecular lipid membranes. A study of low frequency Maxwell-Wagner impedance dispersion.Biochim. Biophys. Acta 373:151–164
6.Cousin, J.L., Motais, R. 1978. Effect of phloretin on chloride permeability; A structure-activity study.Biochim. Biophys. Acta 507:531–538
7.Czech, M.P., Lynn, D.G., Lynn, W.S. 1973. Cytochalasin B-sensitive 2-deoxyD-glucose transport in adipose cell ghosts.J. Biol. Chem. 248:3636–3641
8.De Levie, R., Rangarajan, S.K., Seelig, P.F., Andersen, O.S. 1979. On the adsorption of phloretin into a black lipid membrane.Biophys. J. 25:295–300
9.Eadie, G.S. 1942. The inhibition of cholinesterase by physostigmine and prostigmine.J. Biol. Chem. 146:85–93
10.Jaffe, H.H., Orchin, M. 1962. Theory and Applications of Ultraviolet Spectroscopy. pp. 556–585. John Wiley & Sons, New York
11.Jennings, M.L., Solomon, A.K. 1976. Interaction between phloretin and the red blood cell membrane.J. Gen. Physiol. 67:381–397
12.Ketterer, B., Neumcke, B., Lauger, P. 1971. Transport mechanisms of hydrophobic ions through lipid bilayer membranes.J. Membrane Biol. 5:225–245
13.Lambrechts, A. 1934. Etude spectrographique de la phlorhizine et de ses derives. Spectra ultraviolet de la phloretine, de la phlorine et de la phloroglucine.Compt. Rend. 198:1852–1854
14.LeBlanc, O.H., Jr. 1970. Single ion conductance in lipid bilayers.Biophys. J. 14:94a
15.LeFevere, P.G. 1961. Sugar transport in the red blood cell: Structure-activity relationships in substrates and antagonists.Pharmacol. Rev. 13:39–70
16.LeFevre, P.G., Marshall, J.K. 1959. The attachment of phloretin and analogues to human erythrocytes in connection with inhibition of sugar transport.J. Biol. Chem. 234:3022–3026
17.Liberman, Ye.A., Topaly, V.P. 1969. Permeability of bimolecular phospholipid membranes for fat soluble ions.Biofizika 14:452–461
18.McClellan, A.L. 1963. Tables of Experimental Dipole Moments. W.H. Freeman, San Francisco
19.McKenzie, H.A., Elliott, W.H. 1969. pH and buffers: Physiological media.In: Data For Biochemical Research. R.M.C. Dawson, D.C. Elliott, W.H. Elliott and K.M. Jones, editors, pp. 475–508. Oxford University Press, United Kingdom
20.McLaughlin, S. 1973. Salicylates and phospholipid bilayer membranes.Nature (London) 243:234–236
21.McLaughlin, S.G.A., Szabo, G., Eisenman, G., Ciani, S.M. 1970. Surface charge and the conductance of phospholipid membranes.Proc. Natl. Acad. Sci. USA 67:1268–1275
22.Melnik, E., latorre, R., Hall, J.E., Tosteson, D.C. 1977. Phloretin-induced changes in ion transport across lipid bilayer membranes.J. Gen. Physiol. 69:243–257
23.Montal, M., Mueller, P. 1972. Formation of bimolecular membranes from lipid monolayers and a study of their electrical properties.Proc. Natl. Acad. Sci. USA 69:3561–3566
24.Owen, J.D. 1974. The effect of phloretin on the potassium conductance inAplysia giant neurons.J. Membrane Biol. 16:65–78
25.Reyes, R., Latorre, R. 1979. Effect of the anesthetics benzyl alcohol and chloroform on bilayers made from monolayers.Biophys. J. 28:259–280
26.Smejtek, P., Paulis-Illangasekare, M. 1979. Modification of ion transport in lipid bilayer membranes in the presence of 2,4-dichlorophenoxyacetic acid. I. Enhancement of cationic conductance and changes of the kinetics of nonactin-mediated transport of potassium.Biophys. J. 26:441–466
27.Szabo, G. 1974. Dual mechanism for the action of cholesterol on membrane permeability.Nature (London) 257:47–49
28.Tanford, C. 1973. The Hydrophobic Effect. John Wiley & Sons, New York
29.Tosteson, M.T., Wieth, J.O. 1979. Tributylin-mediated exchange diffusion of halides in lipid bilayers.J. Gen. Physiol. 73:789–800
30.Verkman, A.S., Solomon, A.K. 1980. Kinetics of phloretin binding to phosphatidylcholine vesicle membranes.J. Gen. Physiol. 15:673–692
31.Wieth, J.O., Dalmark, M., Gunn, R.B., Tosteson, D.C. 1973. The transfer of monovalent inorganic anions through the red cell membrane.In: Erythrocytes, Thrombocytes, Leukocytes. E. Gerlacher, K. Moser, E. Deuth and W. Wilmanns, editors. pp. 71–76. Georg Thieme Verlag, Stuttgart