About Synephrine

Synephrine, or, more specifically, p-synephrine, is an alkaloid, occurring naturally in some plants and animals, and also in approved drugs products as its m-substituted analog known as neo-synephrine.

p-Synephrine (or formerly Sympatol and oxedrine [BAN]) and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine

Synephrine (or oxedrine) is extracted from the immature fruits of Citrus aurantium, and its common names are Bitter Orange, Sour Orange, and Zhi shi.
Synephrine usually is used as a drug for weight loss. It has gained significant popularity as an alternative , a related substance which has been made illegal or restricted in many countries due to its use as a precursor in the illicit manufacture of the highly addictive substance In application of traditional Chinese medical science, it is used to dispel bloating and a lump in the abdomen and phlegm, and to cureedema, constipation, gastroptosis, prolapse of uterus and rectocele.

It works on Anti- tumour, preventing osteoporosis, reducing cholesterin and protecting heart.Also it is used for nerve protection and preventing diseases of degeneration of nerve, relieving menopausal symptoms of women, improving bone metabolism and protecting cardiovascular system, etc.

Weight Loss
Citrus aurantium contains the plant chemical, synephrine, which is similar to epinephrine in its chemical structure, and is the reason citrus aurantium has been used in weight loss products after was taken off the market. Synephrine stimulates the nervous system, and is used to decrease appetite.

Citrus aurantium is used in herbal medicines as a general digestive tonic and can be prescribed for indigestion, constipation, low stomach acid, nausea, flatulence and stomach cramps.

Citrus aurantium is one of many plants that can be used for the extraction of Orange Blossom oil and Orange Flower water. It also can be found under the name Neroli petalae, though it is far less fragrant than true Neroli oil.


1) As a dietary supplement designed to support calorie burning (thermogenesis) and resulting weight loss.
2) It also helps to clean the blood and has been reported to dissolve kidney stones.

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Physical Analysis  
DescriptionWhite PowderComplies
AssaySynephrine 98% (HPLC)98.12%
Mesh Size100 % pass 80 meshComplies
Ash≤ 5.0%3.85%
Loss on Drying≤ 5.0%3.45%
Chemical Analysis  
Heavy Metal≤ 10.0 mg/kgComplies
Pb≤ 2.0 mg/kgComplies
As≤ 1.0 mg/kgComplies
Hg≤ 1.0 mg/kgComplies
Microbiological Analysis  
Residue of PesticideNegativeNegative
Total Plate Count≤ 1000cfu/gComplies
Yeast&Mold≤ 100cfu/gComplies


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